MONOCLONAL ANTIBODY MICROARRAY

摘要

The present invention relates generally to the field monoclonal antibody microarrays and their use including the detection and differential expression between abnormal cells and normal cells using monoclonal antibody microarrays. These microarrays and methods enable protein profiling of different sources of samples such as tumor tissue, drug-treated cells, human cells infected with different pathogens (parasites, virus) etc. The protein expression profile of clinical samples may allow us to identify disease markers and enable the development of new anti-disease drugs. Furthermore the correlation of protein expression profile with clinical symptoms may allow us to use the antibody microarray as a diagnostic and/or prognostic tool for different diseases. The invention further relates to the identification of proteins differentially expressed in adenocarcinoma as compared to borderline tumor.