发明名称 STABLE BIOTINYLATED BIOMOLECULE COMPOSITION AND METHOD
摘要 PROBLEM TO BE SOLVED: To provide compositions and methods for biotinylated biomolecules, such as enzymes. SOLUTION: The compositions include a biotinylated biomolecule, a biomolecule protectant, a buffer, a bulking agent selected from one or more water soluble, nonionic polymers and preferably a terminal sterilization protectant. The compositions can be utilized either as aqueous solutions or preferably in dried form, e.g., as a lyophilized, powder cake. They have applicability in any case where avidin/biotin technology is used and are particularly important as compositions containing a thrombin-like enzyme. COPYRIGHT: (C)2008,JPO&INPIT
申请公布号 JP2007295936(A) 申请公布日期 2007.11.15
申请号 JP20070207925 申请日期 2007.08.09
申请人 BRISTOL MYERS SQUIBB CO 发明人 BURTON STEVEN J;PEARSON JAMES C;EDWARDSON PETER A D;MENZIES ALAN
分类号 C12N9/96;G01N33/53;A61K9/19;A61K38/00;A61K38/43;A61K38/46;A61K47/04;A61K47/10;A61K47/18;A61K47/22;A61K47/26;A61K47/32;A61K47/34;A61K47/36;A61K47/42;A61K47/48;A61L2/00;C07D495/04;C07K14/75;C07K17/04;C07K17/06;C12N9/00;C12N9/48;C12N11/06;C12P21/00;C12P21/02;G01N33/531;G01N33/543 主分类号 C12N9/96
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