<p>The present invention provides antibodies comprising an antigen recognition domain that specifically binds to a metal chelate: mutant antibodies comprising a reactive site not present in the wild-type of the antibody, wherein the reactive site is in a position proximate to or within the antigen recognition domain; and methods of using such antibodies to diagnose and treat disease.</p>
申请公布号
WO2007131242(A2)
申请公布日期
2007.11.15
申请号
WO2007US68414
申请日期
2007.05.07
申请人
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA;MEARES, CLAUDE, F.;BUTLIN, NATHANIEL, G.