METHODS AND COMPOSITIONS FOR SELECTING siRNA OF IMPROVED FUNCTIONALITY
摘要
Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rational design, one can maximize the generation of an effective gene silencing reagent, as well as methods for silencing genes. Methods, compositions, and kits generated through rational design of siRNAs are disclosed.
申请公布号
WO2006006948(A3)
申请公布日期
2007.11.15
申请号
WO2004US14885
申请日期
2004.05.12
申请人
DHARMACON, INC.;LEAKE, DEVIN;REYNOLDS, ANGELA;KHVOROVA, ANASTASIA;MARSHALL, WILLIAM;FEDOROV, YURIY;READ, STEVEN
发明人
LEAKE, DEVIN;REYNOLDS, ANGELA;KHVOROVA, ANASTASIA;MARSHALL, WILLIAM;FEDOROV, YURIY;READ, STEVEN