发明名称 |
MEDICAL DEVICE HAVING COATING WITH ZEOLITE DRUG RESERVOIRS |
摘要 |
A medical device having a drug-eluting coating that includes a pharmaceutical compound or, more generally, a therapeutic material housed within pores of a zeolite carrier. The zeolite carrier has an open porous structure with reservoirs for holding the therapeutic material. The therapeutic material loaded zeolites may be suspended or dispersed within a bioerodible polymer matrix to provide controlled delivery of the therapeutic material. Zeolite drug carriers may have enhanced or optimally engineered pore sizes for a particular therapeutic material and release profile. Along with a therapeutic material, reservoirs of a zeolite drug delivery system may include a release agent. The release agent may be used to entrap the therapeutic material until such time as a triggering condition is met that prompts the release agent to activate and thereby release the therapeutic material from the zeolite reservoir. |
申请公布号 |
WO2007130786(A2) |
申请公布日期 |
2007.11.15 |
申请号 |
WO2007US66928 |
申请日期 |
2007.04.19 |
申请人 |
MEDTRONIC VASCULAR, INC.;FRANCIS, RICHARD |
发明人 |
FRANCIS, RICHARD |
分类号 |
A61L31/10;A61L31/14;A61L31/16 |
主分类号 |
A61L31/10 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|