| 发明名称 |
Substituted piperazines and methods of use |
| 摘要 |
Selected substituted piperazine compounds are effective for prophylaxis and treatment of diseases, such as obesity and the like. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving activation of the melanocortin receptor. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.
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| 申请公布号 |
US2007265248(A1) |
申请公布日期 |
2007.11.15 |
| 申请号 |
US20050116759 |
申请日期 |
2005.04.27 |
| 申请人 |
AMGEN INC. |
发明人 |
FOTSCH CHRISTOPHER H.;ARASASINGHAM PREMILLA;BO YUNXIN;CHEN NING;GOLDBERG MARTIN H.;HAN NIANHE;HSIEH FENG-YIN;KELLY MICHAEL G.;LIU QINGYIAN;NORMAN MARK H.;SMITH DUNCAN M.;STEC MARKIAN;TAMAYO NURIA;XI NING;XU SHIMIN;DOHERTY ELIZABETH M. |
| 分类号 |
A61K31/4965;C07D295/18;A61K31/495;A61K31/496;A61K31/497;A61K31/5377;A61K31/551;A61K38/00;A61P3/04;A61P3/10;A61P43/00;C07D205/04;C07D207/08;C07D207/09;C07D209/14;C07D209/18;C07D209/42;C07D211/26;C07D211/60;C07D211/62;C07D213/38;C07D213/81;C07D213/82;C07D215/48;C07D217/06;C07D217/14;C07D217/26;C07D233/54;C07D233/64;C07D243/08;C07D295/185;C07D317/60;C07D317/68;C07D319/16;C07D319/18;C07D401/00;C07D401/12;C07D403/12;C07D407/00;C07D409/12;C07D413/12;C07D417/12;C07D451/02;C07D487/08;C07K5/06;C07K5/078 |
主分类号 |
A61K31/4965 |
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