PROCESS FOR THE DEPROTECTION OF PROTECTED AMINES

摘要

The present invention relates to a process for the deprotection of protected amine compounds, wherein the protected amine compound is contacted with an electrophilic oxidating agent that is optionally formed in situ, said electrophilic oxidating agent being selected from the group of I<SUB>2</SUB>, Br<SUB>2</SUB>, Cl<SUB>2</SUB> and compounds comprising a halogen atom having a formal oxidation state of 1+, 3+, 5+ or 7+, provided that the electrophilic oxidating agent is not iodobenzene diacetate. The process can be conveniently employed in the synthesis of 1 ,3-amino alcohols, ß-amino acids and heterocyclic compounds, in particular ß-amino acids.