INDUCTION OF INTRACELLULAR AND SECRETED GROWTH INHIBITORS AND PARACRINE TUMOR-SUPPRESSIVE ACTIVITY BY RAR LIGANDS
摘要
<p>The invention relates to the induction of senescence in neoplastic cells. More particularly, the invention relates to the use of small molecule compounds to mediate such induction of senescence. The invention provides methods for identifying such compounds, and methods for using the compounds.</p>
申请公布号
WO2007130469(A2)
申请公布日期
2007.11.15
申请号
WO2007US10657
申请日期
2007.05.02
申请人
ORDWAY RESEARCH INSTITUTE, INC.;CHEN, YUHONG;RONINSON, IGOR, B.