发明名称 NON-NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS
摘要 Compounds of Formula (I): are HIV reverse transcriptase inhibitors, wherein R<SUP>1</SUP>, R<SUP>2</SUP>, R<SUP>3</SUP>, R<SUP>4</SUP>and R<SUP>5</SUP> are defined herein. The compounds of Formula (I) and their pharmaceutically acceptable salts are useful in the inhibition of HIV reverse transcriptase, the prophylaxis and treatment of infection by HIV and in the prophylaxis, delay in the onset, and treatment of AIDS. The compounds and their salts can be employed as ingredients in pharmaceutical compositions, optionally in combination with other antivirals, immunomodulators, antibiotics or vaccines.
申请公布号 WO2007002481(A3) 申请公布日期 2007.11.15
申请号 WO2006US24611 申请日期 2006.06.23
申请人 MERCK & CO., INC.;LINDSLEY, CRAIG, W.;LEISTER, WILLIAM, H.;WOLKENBERG, SCOTT, E. 发明人 LINDSLEY, CRAIG, W.;LEISTER, WILLIAM, H.;WOLKENBERG, SCOTT, E.
分类号 A61K31/70 主分类号 A61K31/70
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