发明名称 |
PYRAZOLE DERIVATIVES AND THEIR USE AS PI3K INHIBITORS |
摘要 |
<p>The invention concerns pyrazole derivatives of Formula( I) or pharmaceutically-acceptable salts thereof, wherein each of R, Ring A, m, R<SUP>1</SUP>, R<SUP>2</SUP> and R<SUP>3</SUP> has any of the meanings defined hereinbefore in the description; processes for their preparation, pharmaceutical compositions containing them and their use in therapy, for example in the treatment of disease mediated by a PI3K enzyme and/or a mTOR kinase.</p> |
申请公布号 |
WO2007129052(A1) |
申请公布日期 |
2007.11.15 |
申请号 |
WO2007GB01619 |
申请日期 |
2007.05.02 |
申请人 |
ASTRAZENECA AB;ASTRAZENECA UK LIMITED;DAVID, LAURENT;FOOTE, KEVIN, MICHAEL;LISIUS, ANNEA |
发明人 |
DAVID, LAURENT;FOOTE, KEVIN, MICHAEL;LISIUS, ANNEA |
分类号 |
C07D401/04;A61K31/44;A61P35/00;C07D417/14 |
主分类号 |
C07D401/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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