发明名称 |
CELL CULTURE |
摘要 |
There is provided a method of retarding differentiation of a biological cell, the method comprising culturing the cell in the presence of an inhibitor of E-cadherin activity. The method is particularly advantageous in retarding the differentiation of stem or progenitor cells, and allows suspension culture of such cells in a manner that enables large scale expansion of cell populations. There is also provided a stem or progenitor cell comprising a construct encoding an inhibitor of E-cadherin activity; and a cell culture medium, for use in the retardation of biological cell differentiation, comprising an inhibitor of E-cadherin activity. |
申请公布号 |
WO2007088372(A3) |
申请公布日期 |
2007.11.15 |
申请号 |
WO2007GB00356 |
申请日期 |
2007.02.02 |
申请人 |
THE UNIVERSITY OF MANCHESTER;WARD, CHRISTOPHER, MICHAEL |
发明人 |
WARD, CHRISTOPHER, MICHAEL |
分类号 |
C12N5/00;C12N5/0735;C12N15/113 |
主分类号 |
C12N5/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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