发明名称 |
PROCESS FOR PREPARING MAYTANSINOID ANTIBODY CONJUGATES |
摘要 |
The invention provides a process for preparing a conjugate comprising a cell binding agent chemically coupled to a drug. The process comprises covalently attaching a linker to a cell binding agent, which then is conjugated to a drug, as well as purification and holding steps, and optionally a tangential flow filtration (TFF) step. |
申请公布号 |
EP1853322(A2) |
申请公布日期 |
2007.11.14 |
申请号 |
EP20060720665 |
申请日期 |
2006.02.10 |
申请人 |
IMMUNOGEN, INC. |
发明人 |
CHARI, RAVI;ZHANG, WEI;MESHULAM, DEBORAH H.;DAI, YONG;WANG, YONG;AMPHLETT, GODFREY W. |
分类号 |
A61K47/48 |
主分类号 |
A61K47/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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