发明名称 |
APPARATUS AND METHOD FOR TRANSDERMAL DELIVERY OF ERYTHROPOETIN-BASED AGENTS |
摘要 |
An apparatus and method for transdermally delivering a biologically active agent comprising a delivery system having a microprojection member (or system) that includes a plurality of microprojections (or array thereof) that are adapted to pierce through the stratum corneum into the underlying epidermis layer, or epidermis and dermis layers. In one embodiment, an Epoetin-based agent is contained in a biocompatible coating that is applied to the microprojection member. In a further embodiment, the delivery system includes a gel pack having an Epoetin-based agent-containing hydrogel formulation that is disposed on the microprojection member after application to the skin of a patient. In an alternative embodiment, the Epoetin-based agent is contained in both the coating and the hydrogel formulation. |
申请公布号 |
EP1853231(A2) |
申请公布日期 |
2007.11.14 |
申请号 |
EP20060720822 |
申请日期 |
2006.02.15 |
申请人 |
ALZA CORPORATION |
发明人 |
AMERI, MAHMOUD;CORMIER, MICHEL, J., N.;MAA, YUH-FUN;DADDONA, PETER |
分类号 |
A61K9/28;A61K38/18 |
主分类号 |
A61K9/28 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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