发明名称 |
CATALYST FOR ASYMMETRIC SYNTHESIS, LIGAND FOR USE THEREIN, AND PROCESS FOR PRODUCING OPTICALLY ACTIVE COMPOUND THROUGH ASYMMETRIC SYNTHESIS REACTION USING THEM |
摘要 |
<p>Compounds represented by the following general formula (1a) or (1b).
A complex comprising a center metal of rhodium and a compound represented by the following general formula (1a) or (1b) as a ligand. A catalyst for optically active beta-substituted carbonyl compound synthesis and catalyst for asymmetric 1, 2 addition reaction being composed of the complex. A method of production of an optically active beta-aryl compound from an alpha, beta- unsaturated compound and an aryl-boronic acid derivative and method of production of an optically active aryl alcohol compound from an aldehyde compound and aryl boronic acid derivatives using the catalyst. A complex comprising a center metal of palladium and a compound represented by the following general formula (1a) or (1b) as a ligand. A catalyst for asymmetric allylic substitution reaction being composed of the complex. A method of production of an optically active dialkyl (1,3-disubstituted propeny)malonate compound from a 1,3- disubstituted ally acetate compound and a dialkyl malonate and method of production of an optically active allylamine compound from a 1,3-disubstituted ally acetate compound and an amine compound. The compounds have not only the versatility of being usable in the synthesis of wide-ranging optically active aryl compounds but also the selectivity and reactivity permitting synthesis with high yield within a short period of time under industrially advantageous mild conditions.</p> |
申请公布号 |
EP1854802(A1) |
申请公布日期 |
2007.11.14 |
申请号 |
EP20060713991 |
申请日期 |
2006.02.17 |
申请人 |
JAPAN SCIENCE AND TECHNOLOGY AGENCY |
发明人 |
MIYAURA, NORIO Y;YAMAMOTO, YASUNORI R. |
分类号 |
C07F9/6574;B01J31/22;C07B53/00;C07C29/44;C07C33/34;C07C33/44;C07C45/70;C07C47/228;C07C49/213;C07C49/563;C07C49/657;C07C49/76;C07C67/24;C07C67/343;C07C69/612;C07C69/618;C07C209/16;C07C211/28;C07F15/00 |
主分类号 |
C07F9/6574 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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