发明名称 |
COMPOSITIONS AND METHODS FOR MODELING SACCHAROMYCES CEREVISIAE METABOLISM |
摘要 |
The invention provides an in silica model for determining a S. cerevisiae physiological function. The model includes a data structure relating a plurality of S. cerevisiae reactants to a plurality of S. cerevisiae reactions, a constraint set for the plurality of S. cerevisiae reactions, and commands for determining a distribution of flux through the reactions that is predictive of a S. cerevisiae physiological function. A model of the invention can further include a gene database containing information characterizing the associated gene or genes. The invention further provides methods for making an in silica S. cerevisiae model and methods for determining a S. cerevisiae physiological function using a model of the invention. The invention provides an in silica model for determining a S. cerevisiae physiological function. The model includes a data structure relating a plurality of S. cerevisiae reactants to a plurality of S. cerevisiae reactions, a constraint set for the plurality of S. cerevisiae reactions, and commands for determining a distribution of flux through the reactions that is predictive of a S. cerevisiae physiological function. A model of the invention can further include a gene database containing information characterizing the associated gene or genes. The invention further provides methods for making an in silica S. cerevisiae model and methods for determining a S. cerevisiae physiological function using a model of the invention. |
申请公布号 |
EP1438580(A4) |
申请公布日期 |
2007.11.14 |
申请号 |
EP20020784306 |
申请日期 |
2002.10.24 |
申请人 |
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA |
发明人 |
PALSSON, BERNHARD, O.;FAMILI, IMANDOKHT;FU, PENGCHENG;NIELSEN, JENS, B.;FORSTER, JOCHEN |
分类号 |
G06F17/30;G06F19/12;G06F19/18 |
主分类号 |
G06F17/30 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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