发明名称 |
Process for producing optically active secondary alcohol |
摘要 |
The present invention provides a method enabling convenient production of an optically active secondary alcohol useful as a pharmaceutical intermediate, particularly an optically active 1,2-diol and an optically active 2-alkanol, from an enantiomer mixture thereof. An oxidizing enzyme source having the capability of selectively oxidizing one enantiomer of secondary alcohol is allowed to act on an enantiomer mixture of secondary alcohol in the presence of a reducing enzyme source having the capability of reverse enantio-selectively reducing a ketone derivative, to convert the enantiomer mixture into a substantially single enantiomer at a theoretical percent recovery of 100%, whereby an optically active secondary alcohol is produced. |
申请公布号 |
EP1854893(A1) |
申请公布日期 |
2007.11.14 |
申请号 |
EP20060714508 |
申请日期 |
2006.02.24 |
申请人 |
KANEKA CORPORATION |
发明人 |
IWASAKI, AKIRA;WASHIDA, MOTOHISA;TAOKA, NAOAKI;MORIYAMA, DAISUKE;HASEGAWA, JUNZOU |
分类号 |
C12P7/04;C12P7/16;C12P7/24;C12P7/40;C12P7/56;C12P41/00 |
主分类号 |
C12P7/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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