摘要 |
<p>A process is described for the preparation of drospirenone, a synthetic steroid with progestogenic, antimineralocorticoid and antiandrogenic activity, useful for preparing pharmaceutical compositions with contraceptive action; comprising the oxidation of 17??-(3-hydroxypropyl)-6??, 7??, 15??, 16??-dimethylene-5??-androstane- 3?? , 5, 17?? -triol.</p> |