发明名称 |
Biomarkers and Methods for Determining Sensitivity to Epidermal Growth Factor Receptor Modulators in Non-Small Cell Lung Cancer |
摘要 |
EGFR biomarkers useful in a method for identifying a mammal that will respond therapeutically to a method of treating cancer comprising administering an EGFR modulator, wherein the method comprises (a) exposing a biological sample from the mammal to the EGFR modulator and (b) measuring in the biological sample the level of the at least one biomarker, wherein a difference in the level of the at least one biomarker measured in (b) compared to the level of the biomarker in a mammal that has not been exposed to the EGFR modulator indicates that the mammal will respond therapeutically to the method of treating cancer.
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申请公布号 |
US2007259375(A1) |
申请公布日期 |
2007.11.08 |
申请号 |
US20050594211 |
申请日期 |
2005.03.28 |
申请人 |
BRISTOL-MYERS SQUIBB COMPANY |
发明人 |
FORD SHIRIN K.;PERKINS NANCY-ANNE;JACKSON DONALD G.;FORD SHIRIN K.;PERKINS NANCY-ANNE;JACKSON DONALD G. |
分类号 |
G01N33/53;C12Q1/68 |
主分类号 |
G01N33/53 |
代理机构 |
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地址 |
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