USE OF SUBSTITUTED GLYCERIN DERIVATIVES FOR PRODUCING A PHARMACEUTICAL PREPARATION

摘要

The invention relates to a compound of formula (I) or pharmaceutically acceptable salts thereof which can be used for producing a pharmaceutical preparation for preventing or treating cancerous diseases, pathological consequences of alcohol abuse, viral hepatitis, steatohepatitis, acute and chronic pancreatitis, toxic renal diseases, hepatic insulin resistance in diabetes mellitus, hepatic damage in Wilson's disease and/or sideroses and/or ischaemic reperfusion damage as an antidote against environmental toxins and medicament intoxication in order to extend the resistance time of medicaments in organisms, and/or for combating toxic side effects of the administration of chemotherapeutics. B₆, B₇ and B₈ are identical or different and represent 0, S, NH, PO₄, Se, SO₄. R₁ is identical to H or a C₆- and/or C₇-to C₂₆- and/or C₂₀-alkyl chain, and R₂, R₃, R₄ and R₅ can be identical or different and represents an H or C₁- to C₃- alkyl, alkanol, alkylamine and/or alkylthiol-group. R₆, R₇ and R₈ can be identical or different and H represents a substituted or unsubstituted C₆- and/or C₇- to C₂₆-alkyl radical, a glucose radical, a positive or negatively charged amino acid radical and a - (CH₂)_n-N⁺(R₉, R₁₀, R₁₁). R₉, R₁₀, R₁₁ is H, methyl-, ethyl- and/or propyl radical, and at least two of R₂, R₃, R₄ and R₅ can together form a polyol radical and n is a whole number from 1 to 5.