AN ANIMAL MODEL AND A METHOD FOR PRODUCING AN ANIMAL MODEL

摘要

The present invention discloses a non-human animal model for a hereditary autosomal dominant disease. The non-human animal model expresses at least o ne phenotype associated with the disease and is obtained by a genetic determ inant. The invention also relates to sperm cells and embryos comprising the genetic determinant for an autosomal dominant disease. Furthermore, methods for producing the non-human animal model, sperm cell, and embryos are disclo sed.