GINKGO BILOBA LEAF EXTRACT HAVING NOVEL COMPOSITION USEFUL FOR PREVENTION OR TREATMENT OF ALZHEIMER'S DISEASE AND PARKINSON'S DISEASE, AND EXTRACTING AND PURIFYING METHOD THEREOF

摘要

The present invention relates to a ginkgo biloba leave extract comprising 10-14 wt% (preferably 11-13 wt% and most preferably 12 wt%) of a terpene trilactone, 20-30 wt% of a ginkgo flavone glycoside and less than 5 ppm of a ginkgolic acid relative to total weight of the extract, which is superior to the conventional ginkgo biloba leave extract comprising the standardized ginkgo biloba extract (German pharmacopoeia 2000) in inhibiting the generation of NO (nitric oxide) and treating Alzheimer's disease and Parkinson's disease, and the present invention also relates to the extraction and purification method thereof and a pharmaceutical composition comprising the same as an active ingredient.