The present invention describes a mutant type Il beta-lactam acylase that is a variant of a model polypeptide with type Il beta-lactam acylase activity whereby the mutant beta-lactam acylase has an at least 1.5-fold improved in vitro beta-lactam acylase activity towards adipyl-7-ADCA in comparison with the model polypeptide with beta-lactam acylase activity.
申请公布号
WO2007073947(A3)
申请公布日期
2007.11.08
申请号
WO2006EP12654
申请日期
2006.12.28
申请人
DSM IP ASSETS B.V.;LAAN VAN DER, JAN METSKE;KERKMAN, RICHARD;BIJLEVELD, WILLEM;GIELESEN, BIANCA
发明人
LAAN VAN DER, JAN METSKE;KERKMAN, RICHARD;BIJLEVELD, WILLEM;GIELESEN, BIANCA