发明名称 |
VIRAL ADJUVANTS |
摘要 |
The present invention provides viral adjuvants for enhancing an immune response to an immunogen. In particular embodiments, the viral adjuvant is an alphavirus adjuvant or a Venezuelan Equine Encephalitis viral adjuvant. Also provided are compositions comprising the viral adjuvant and an immunogen, and pharmaceutical formulations comprising the viral adjuvant or compositions of the invention in a pharmaceutically acceptable carrier. Further provided are methods of producing an immune response against an immunogen in a subject comprising administering the immunogen and a viral adjuvant of the invention to the subject. |
申请公布号 |
WO2006085983(A3) |
申请公布日期 |
2007.11.08 |
申请号 |
WO2005US24424 |
申请日期 |
2005.07.08 |
申请人 |
UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL;JOHNSTON, ROBERT E.;THOMPSON, JOSEPH M. |
发明人 |
JOHNSTON, ROBERT E.;THOMPSON, JOSEPH M. |
分类号 |
A61K39/42;A61K39/193;A61K45/00 |
主分类号 |
A61K39/42 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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