THERMOSTABLE DNA POLYMERASE FROM THERMOTOGA NAPHTHOPHILA AND THERMOTOGA PETROPHELLIA

摘要

Disclosed are isolated, thermostable DNA polymerases from Thermotoga naphthophila and Thermotoga petrophellia respectively. These enzymes are useful for DNA sequencing, and polymerase chain reaction. Included within the scope of the present invention are various mutants (deletion and substitution) that retain thermostability and the ability to replicate DNA with substantially the same efficiency as the native Thermotoga naphthophila or Thermotoga petrophellia polymerase.