发明名称 |
Transgenic Mammals and Cell Lines for the Identification of Glutamate Transporter Modulators |
摘要 |
The invention includes a transgenic, non-human mammal useful for identifying candidate compounds for treating neurological and/or psychiatric disorders. Incorporated into the genome of the transgenic mammal is a transgene comprising a glutamate transporter promoter operatively linked to a reporter gene. The transgenic non-human mammal and cells isolated therefrom can be used as an in vivo model for the identification of candidate compounds useful for the treatment of neurological and/or psychiatric disorders.
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申请公布号 |
US2007259825(A1) |
申请公布日期 |
2007.11.08 |
申请号 |
US20050661624 |
申请日期 |
2005.08.31 |
申请人 |
JOHNS HOPKINS UNIVERSITY |
发明人 |
ROTHSTEIN JEFFREY D.;REGAN MELISSA;TOAN SHUY V. |
分类号 |
A01K67/027;A61K31/70;C12N5/06;C12Q1/68 |
主分类号 |
A01K67/027 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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