| 发明名称 |
Methods for the treatment of flavivirus infection, molecules and uses thereof |
| 摘要 |
The present invention is related to a method for blocking the infection of cells by dengue virus, based on interfering the direct interaction of the viral envelope protein with a cellular receptor or its indirect interaction with said cellular receptor through a carrier protein, as well as related uses; wherein said cellular receptor is the alpha-2 macroglobulin receptor, also known as the low density receptor-related protein or as CD91, and said carrier protein is human alpha-2 macroglobulin. |
| 申请公布号 |
AU2007246076(A1) |
申请公布日期 |
2007.11.08 |
| 申请号 |
AU20070246076 |
申请日期 |
2007.04.26 |
| 申请人 |
CENTRO DE INGENIERIA GENETICA Y BIOTECNOLOGIA |
发明人 |
NORALVIS FLEITAS SALAZAR;ANIA CABRALES RICO;OSVALDO REYES ACOSTA;VIVIAN HUERTA GALINDO;ANIEL SANCHEZ PUENTE;HILDA ELISA GARAY PEREZ;ALEJANDRO MIGUEL MARTIN DUNN;VLADIMIR ARMANDO BESADA PEREZ;GLAY CHINEA SANTIAGO;MONICA SARRIA NUNEZ;GABRIEL RAMON PADRON PALOMARES;ALEXIS MUSACCHIO LASA;LUIS JAVIER GONZALEZ LOPEZ;OSMANY GUIROLA CRUZ;PATRICIA GABRIELA TOLEDO MAYORA |
| 分类号 |
A61K39/00 |
主分类号 |
A61K39/00 |
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