| 发明名称 |
INHIBITORS OF CATHEPSIN S |
| 摘要 |
The present invention provides compounds, compositions and methods for the selective inhibition of cathepsin S. In a preferred aspect, cathepsin S is selectively inhibited in the presence of at least one other cathepsin isozyme. The present invention also provides methods for treating a disease state in a subject by selectively inhibiting cathepsin S.
|
| 申请公布号 |
US2007259873(A1) |
申请公布日期 |
2007.11.08 |
| 申请号 |
US20070777879 |
申请日期 |
2007.07.13 |
| 申请人 |
IRM LLC |
发明人 |
LIU HONG;ALPER PHILLIP B.;KARANEWSKY DONALD S. |
| 分类号 |
A61K31/4184;A61K;A61K31/325;A61K31/40;A61K31/415;A61K31/4172;A61K31/421;A61K31/426;A61K31/454;A61K31/496;A61K31/537;A61K31/5377;A61K31/54;A61P11/06;A61P19/02;A61P25/00;A61P25/28;C07D231/12;C07D235/06;C07D235/08;C07D413/12 |
主分类号 |
A61K31/4184 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
