| 摘要 |
An object of the present invention is to provide a method for efficiently producing a high-purity fluorinated proline derivative with high yield. A method tor producing a compound represented by the general formula (2),
(In the formula, R1 represents an unsubstituted or substituted alkyl group having 1 to 6 carbon atoms or the like, and R2 represents an unsubstituted or substituted alkyl group having 1 to 6 carbon atoms or the like, and R3 represents a hydroxyl group or the like) wherein a compound represented by the general formula (1)
(In the formula, R1 and R2 are defined as in the general formula (1)) is reacted with a fluorination agent to obtain a reaction product containing the compound represented by the general formula (2) and a by-products; and bringing chlorine, bromine, iodine, hypochlorous acid, hypochlorite, hypobromous acid, hypobromite or N-halogenosuccinimide into action on the reaction product to chemically change the by-product.
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