发明名称 |
PLATELET-DERIVED MICROPARTICLES AS A NOVEL DIAGNOSIS MAKER FOR A CARDIOVASCULAR DISEASE |
摘要 |
The present invention is directed to a method for evaluating whether coronary artery disease has progressed in a patient previously diagnosed as having the disease, wherein the method includes: (a) obtaining a biological sample from the patient at a first time point and a second time point; (b) detecting the level of platelet-derived microparticles (PDMPs) or a fragment thereof, in the first time point sample and the second time point sample with an antibody to PDMPs or a fragment thereof; wherein an increase in a level of the PDMPs in the second time point sample in comparison to a level in the first time point sample is indicative of progression of coronary artery disease. |
申请公布号 |
EP1851541(A1) |
申请公布日期 |
2007.11.07 |
申请号 |
EP20050708556 |
申请日期 |
2005.02.21 |
申请人 |
SAGA UNIVERSITY |
发明人 |
NODE, KOICHI;INOUE, TERUO |
分类号 |
G01N33/50;A61B5/00 |
主分类号 |
G01N33/50 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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