发明名称 INHIBITORS OF 11-BETA-HYDROXY STEROID DEHYDROGENASE TYPE 1.
摘要 <p>The present invention relates to compounds with the formula (I), (II), (III) or (IV): (I) (II), (III), or (IV), wherein R1, R2, R3, R4, R5, R6, R7, X and Z are as defined herein, and also to pharmaceutical compositions comprising the compounds, as well as methods of use of the compounds for treatment of disorders associated with human 11-beta-hydroxysteroid dehydrogenase type 1 enzyme and for the preparation of a medicament which acts on the human 11-beta-hydroxysteroid dehydrogenase type 1 enzyme.</p>
申请公布号 MXPA06013657(A) 申请公布日期 2007.11.07
申请号 MX2006PA13657 申请日期 2005.05.24
申请人 AMGEN INC. 发明人 CHRISTOPHER H. FOTSCH;GUOLIN CAI;LARS JOHANSSON;AIWEN LI.;NIANHE HAN;QI HUANG;CHESTER CHENGUANG YUAN;JERK VALLGARDA;MEREDITH WILLIAMS;QINGYIAN LIU;MARTIN HENRIKSSON;EVERT HOMAN;ERIC BERCOT;TEGLEY CHRISTOPHER;DAVID JEAN ST.;MICHAEL D. BARTBERGER;GEORGE A. MONIZ;MATTHEW J. FRIZZLE;RANDALL HUNGATE W.
分类号 C07D277/54;A61K31/42;A61K31/426;A61P3/00;A61P3/04;A61P3/06;A61P3/10;A61P19/10;A61P25/24;A61P25/28;A61P29/00;A61P31/12;C07D;C07D263/48;C07D277/42;C07D277/60;C07D413/14;C07D417/06;C07D417/12;C07D417/14;C07D513/10;C07F7/18 主分类号 C07D277/54
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