| 发明名称 |
METABOLITES FOR NK-1 ANTAGONISTS FOR EMESIS |
| 摘要 |
The present invention relates to compounds of the general formula (I) wherein R is methyl; and R1 is 4-methyl-4-oxy-piperazin-l-yl; or R is CH2OH and R1 is 4-methyl-piperazin-l-yl or is 4-methyl-4-oxy-piperazin-l-yl; and to pharmaceutically acceptable acid addition salts thereof for the treatment of NK-I receptor related diseases.
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| 申请公布号 |
KR20070107146(A) |
申请公布日期 |
2007.11.06 |
| 申请号 |
KR20077021748 |
申请日期 |
2007.09.21 |
| 申请人 |
F. HOFFMANN-LA ROCHE AG |
发明人 |
FUNK CHRISTOPH;HOFFMANN TORSTEN;KOBLET ANDREAS |
| 分类号 |
C07D401/04;A61K31/4418;A61K31/444;C07D213/75 |
主分类号 |
C07D401/04 |
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