发明名称 |
3-amido-1,2-benzoisoxazole derivatives, process for preparation, and use thereof |
摘要 |
The present invention relates to 3-amido-1,2-benzoisoxazole derivatives and their salts represented by formula 1, processes for preparation and usees thereof. More particularly, it relates to a method for improving its bioavailability introducing amino acid residue to the amine group of a 3-amido-1,2-benzoisoxazole. The compounds according to the present invention are used as an antagonist against Leukotriene-B-4 receptor, an inhibitor or therapeutics of osteoroposis, thus inhibiting osteolysis and stimulating osteogensis.
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申请公布号 |
US7291638(B2) |
申请公布日期 |
2007.11.06 |
申请号 |
US20040493702 |
申请日期 |
2004.04.27 |
申请人 |
DONGWHA PHARM. IND. CO., LTD. |
发明人 |
LEE JIN-SOO;AHN SEOK-HOON;JIN YOUNG-GOO;JIN SANG-MI;KU SAE-KWANG;RYE JEI-MAN;CHUNG YONG-HO;KIM EUN-JOO;CHO SUN-KI |
分类号 |
A61K31/42;A61K31/423;A61P19/10;C07D261/20 |
主分类号 |
A61K31/42 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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