发明名称 6H-oxazolo[4,5-e]indole derivatives as nicotinic acetylcholine receptor ligands and/or serotonergic ligands
摘要 Compounds of the formula I in which R<SUP>1</SUP>, R<SUP>2</SUP>, R<SUP>3 </SUP>and R<SUP>4 </SUP>are as defined in claim 1, are ligands of the nicotinic acetylcholine receptor and/or serotonergic ligands and are suitable for the prophylaxis or treatment of psychoses, schizophrenia, depression, anxiety states, dementia, in particular Alzheimer's disease and Lewy bodies dementia, neurodegenerative disorders, Parkinson's disease, amyotrophic lateral sclerosis, Huntington's disease, Tourette's syndrome, learning and memory restrictions, bulimia anorexia nervosa or other eating disorders, compulsvie behaviour, premenstrual syndrome, age-induced memory impairment, amelioration of withdrawal symptoms in nicotine dependence, strokes or brain damage by toxic compounds, and for the treatment of disorders which are characterised by an excess of circulating serotonin or by serotonergic hyperactivity
申请公布号 US7291633(B2) 申请公布日期 2007.11.06
申请号 US20030476306 申请日期 2003.10.29
申请人 MERCK PATENT GMBH 发明人 SCHIEMANN KAI;BOETTCHER HENNING;LEIBROCK JOACHIM
分类号 A61K31/424;A61K31/439;A61K31/445;A61K31/454;A61K31/496;A61K31/5377;A61P1/14;A61P3/04;A61P5/24;A61P15/00;A61P21/00;A61P25/00;A61P25/14;A61P25/16;A61P25/18;A61P25/22;A61P25/24;A61P25/28;A61P25/34;A61P43/00;C07D401/14;C07D413/14;C07D498/02;C07D498/04;C07D519/00 主分类号 A61K31/424
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