ANTIBIOTIC/BONE MORPHOGENIC PROTEIN FORMULATION AND METHOD OF TREATMENT

摘要

A formulation comprised of particles which may be in groups and are comprised of a biocompatible polymer and an antimicrobial drug for controlled release of the drug is disclosed. The particles may be in an aqueous solution comprising thrombin and be dispersed in a gel. The formulation is administered to an area such as an open wound having an orthopedic implant therein and provides a therapeutically effective level of drug to the patient over a therapeutically effective period of time.