| 摘要 |
An iontophoresis device which allows excellent transdermal absorption of an anionically chargeable physiologically active substance is provided. The iontophoresis device comprises a cathode ( 25 ) and an interface ( 31 ) or ( 32 ) composed of a cationically chargeable membrane, wherein an anionically chargeable physiologically active substance (drug) ( 10 ) is placed between the cathode ( 25 ) and the interface ( 31 ) or in the interface ( 32 ). A wall member ( 13 ) with an adhesive layer ( 12 ) in the bottom is placed around an absorbent ( 11 ), and a support ( 15 ) having an opening ( 14 ) in the center is placed on the absorbent ( 11 ) and the wall member ( 13 ). When the device is used, the dissolution liquid for the drug is supplied to the absorbent ( 11 ) through the opening ( 14 ). The absorbent ( 11 ) and the interface ( 31 ) or ( 32 ) become wet with the dissolution liquid and the drug ( 10 ) is activated uniformly.
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