发明名称 ANTIFUNGAL AND ANTIPARASITIC INDOLOQUINOLINE DERIVATIVES
摘要 <p>A compound having the formula: (I), (II), (III), or (IV) wherein: R is an electron withdrawing or electron moiety; R&lt;SUB&gt;5&lt;/SUB&gt; and R&lt;SUB&gt;10&lt;/SUB&gt; may be the same or different and are a straight or branched 1-5 carbon or heteroatom chain substituted terminally by a cycloalkyl or aromatic ring, or other structural isomer or complex thereof; n is the position of substitution of R; Z is N-R&lt;SUB&gt;10&lt;/SUB&gt;, O, S, S=O, CH&lt;SUB&gt;2&lt;/SUB&gt; or C=O; y is 1-5 and Q is Z or NH, with the proviso that, where Z is NH, N-CH&lt;SUB&gt;3&lt;/SUB&gt;, S or O and R&lt;SUB&gt;n&lt;/SUB&gt; is H, R&lt;SUB&gt;5&lt;/SUB&gt; may not be CH&lt;SUB&gt;3&lt;/SUB&gt;; as well as quaternary ammonium salts thereof and their use as pharmacological compositions and for methods of treatment.</p>
申请公布号 WO2007123732(A2) 申请公布日期 2007.11.01
申请号 WO2007US07976 申请日期 2007.03.30
申请人 FLORIDA A & M UNIVERSITY;ABLORDEPPEY, SETH, Y. 发明人 ABLORDEPPEY, SETH, Y.
分类号 A61K31/4745;A61K31/4704;A61K31/4706;C07D471/02 主分类号 A61K31/4745
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