| 摘要 |
<p>The present invention provides methods for improving the efficiency of methylation detection. The present invention provides improvements from current technologies via increased efficiency of template denaturation and bisulfite conversion reaction, also significant time savings in sample preparation, recovery, as well as increased efficiency of desulfonation. These methods facilitate rapid analysis of research and clinical samples and enhance the ability to process high-through put sample preparations. The methods are applicable to essentially all methylation detection procedures and also to the analysis of methylation patterns from various species.</p> |
