发明名称 |
LIPOPLEX FORMULATIONS FOR SPECIFIC DELIVERY TO VASCULAR ENDOTHELIUM |
摘要 |
<p>The present invention is related to a lipid composition contained in and/or containing a carrier comprising at least a first lipid component, at least a first helper lipid, and a shielding compound which is optionally removable from the lipid composition under in vivo conditions, whereby the lipid composition containing carrier has an osmolality of about 50 to 600 mosmole/kg, preferably about 250 - 350 mosmole/kg, and more preferably about 280 to 320 mosmole/kg, and/or whereby liposomes formed by the first lipid component and/or one or both of the helper lipid and the shielding compound in the carrier have a particle size of about 20 to 200 nm, preferably about 30 to 100 nm, and more preferably about 40 to 80 nm.</p> |
申请公布号 |
WO2007121947(A1) |
申请公布日期 |
2007.11.01 |
申请号 |
WO2007EP03496 |
申请日期 |
2007.04.20 |
申请人 |
ATUGEN AG;KAUFMANN, JOERG;KEIL, OLIVER;SANTEL, ANSGAR |
发明人 |
KAUFMANN, JOERG;KEIL, OLIVER;SANTEL, ANSGAR |
分类号 |
A61K9/127;A61K47/48 |
主分类号 |
A61K9/127 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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