Complement-based analyte assay

摘要

An assay in which the presence or quantity of analyte in a sample is determined by treating the sample to form a reagent complex in which the analyte is bound to antibody to form an immune complex that is fixed by complement. The reagent complex is captured using complement antibody, and detected using a labeled ligand for the antibody. In one embodiment, the assay is applied to detect endotoxin in patient plasma.