PHARMACEUTICAL SOLUTION FORMULATIONS FOR PRESSURISED METERED DOSE INHALERS

摘要

The invention relates to the use a solution formulation for pressurized metered dose inhalers able of providing therapeutical doses of two or more active drug substances to the lung for the manufacture of a medicament for the prevention or treatment of a severe broncho-pulmonary disease, wherein all the active drug substances are fully dissolved in the formulation as well as the two or more active drug substances are delivered with substantially the same particle size distribution.