DEVICES AND METHODS FOR INTRAVASCULAR DRUG DELIVERY

摘要

A catheter configured for delivering an agent to a patient's vessel wall, having self-expanding frame, and a method of delivering an agent to a patient's vessel wall. A first catheter has an elongated shaft with an agent delivery lumen and self-expanding frame on a distal shaft section formed of plurality of hollow tubes having joined first ends and free second ends, the free end of each hollow tube having an agent delivery port in fluid communication with the shaft agent delivery lumen and having a hooked tip configured for penetrating the vessel wall in the expanded configuration. Another catheter has a frame around the outer surface of a lining member such as a balloon or a tubular sleeve, such that the frame expanded against the vessel wall and the lining member together define a plurality of pockets between the vessel wall and the outer surface of the lining member.