发明名称 |
Antimicrobial preservatives to achieve multi-dose formulation using beta-cyclodextrins for liquid dosage forms |
摘要 |
The present invention is directed to pharmaceutical compositions containing a therapeutically effective amount of an Active Pharmaceutical Ingredient (“API”), a pharmaceutically acceptable cyclodextrin and a pharmaceutically acceptable preservative. The invention is also directed to pharmaceutical compositions of the compounds of Formula (I) wherein R2 is selected from the group consisting of methyl, ethyl, isopropyl, sec-butyl and tert-butyl and a pharmaceutically acceptable cyclodextrin and preservative. Formula (I): In particular, the invention is directed to pharmaceutical compositions of the compound of Formula 1a, and a pharmaceutically acceptable cyclodextrin and a preservative. |
申请公布号 |
ZA200605148(B) |
申请公布日期 |
2007.10.31 |
申请号 |
ZA20060005148 |
申请日期 |
2006.06.22 |
申请人 |
PFIZER PRODUCTS INC. |
发明人 |
ADAMI, ROGER CHRISTOPHER;WOOD, JULIA ANN;DAVID, FREDERICK |
分类号 |
A61K;A61K9/00;A61K47/00;A61K47/10;A61K47/40;A61K47/48 |
主分类号 |
A61K |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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