SINGLE NUCLEOTIDE POLYMORPHISM DETECTION FROM UNAMPLIFIED GENOMIC DNA

摘要

The present invention provides methods, compositions and systems for the specific and selective detection of multiple single nucleotide polymorphisms (SNPs) from genomic DNA. Importantly, the inventive systems and methods eliminate the need for costly, time- and labor-intensive gene amplification that is generally carried out prior to SNP detection. Also provided are kits useful to perform the inventive methods.