发明名称 |
MULTIPARTICULATE CONTROLLED RELEASE SELECTIVE SEROTONIN REUPTAKE INHIBITOR FORMULATIONS |
摘要 |
A multiparticulate controlled release selective serotonin reuptake inhibitor (SSRI) formulation for oral administration comprises particles of said SSRI or a pharmaceutically acceptable salt thereof coated with rate-controlling polymer which allows controlled release of said SSRI, over a period of not less than about 12 hours following oral administration. The formulation, which contains for example fluvoxamine or a pharmaceutically acceptable salt thereof, is suitable for once or twice daily administration. The formulation can comprise a blend of two or more populations of particles, pellets or mini-tablets having different in vitro and/or in vivo release characteristics. |
申请公布号 |
PT1178780(E) |
申请公布日期 |
2007.10.25 |
申请号 |
PT20000925548T |
申请日期 |
2000.05.10 |
申请人 |
ELAN PHARMA INTERNATIONAL LIMITED |
发明人 |
PAUL STARK;THERESA ANN JEARY;COUNTY ROSCOMMON ATHLONE |
分类号 |
A61K9/50;A61K9/52;A61K31/135;A61K31/137;A61K31/138;A61K31/15;A61K31/343;A61K31/4525;A61K31/496;A61K45/00;A61K47/32;A61P25/18;A61P25/24 |
主分类号 |
A61K9/50 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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