发明名称 Bcma Polypeptides and Uses Thereof
摘要 The present invention relates to polypeptides that inhibit APRIL and/or BAFF binding to BCMA, nucleic acid molecules encoding the polypeptides, and compositions comprising the polypeptides. The present invention also relates to methods for treating an immune-related disease or cancer using the polypeptides and compositions of the invention. The present invention also relates to methods for identifying inhibitors of APRIL/BAFF binding to BCMA and APRIL/BAFF signaling.
申请公布号 US2007249530(A1) 申请公布日期 2007.10.25
申请号 US20040587370 申请日期 2004.08.04
申请人 GENENTECH, INC. 发明人 KELLEY ROBERT F.;PATEL DARSHANA R.
分类号 A61K48/00;A61K38/00;C07H21/04;C07K14/00;C07K14/705;C12N5/06;C12N15/00;C12P1/04;G01N33/53 主分类号 A61K48/00
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