发明名称 |
Bcma Polypeptides and Uses Thereof |
摘要 |
The present invention relates to polypeptides that inhibit APRIL and/or BAFF binding to BCMA, nucleic acid molecules encoding the polypeptides, and compositions comprising the polypeptides. The present invention also relates to methods for treating an immune-related disease or cancer using the polypeptides and compositions of the invention. The present invention also relates to methods for identifying inhibitors of APRIL/BAFF binding to BCMA and APRIL/BAFF signaling.
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申请公布号 |
US2007249530(A1) |
申请公布日期 |
2007.10.25 |
申请号 |
US20040587370 |
申请日期 |
2004.08.04 |
申请人 |
GENENTECH, INC. |
发明人 |
KELLEY ROBERT F.;PATEL DARSHANA R. |
分类号 |
A61K48/00;A61K38/00;C07H21/04;C07K14/00;C07K14/705;C12N5/06;C12N15/00;C12P1/04;G01N33/53 |
主分类号 |
A61K48/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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