| 发明名称 |
PROCESS FOR THE PREPARATION OF [(1R), 2S]-2-AMINOPROPIONIC ACID 2-[4-(4-FLUORO-2-METHYL-1H-INDOL-5-YLOXY)-5-METHYLPYRROLO[2,1-f][1,2,4]TRIAZIN-6-YLOXY]-1-METHYLETHYL ESTER |
| 摘要 |
The invention relates to an improved process for preparing [(1R),2S]-2-aminopropionic acid 2-[4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yloxy]-1-methylethyl ester of the formula: Compound I has been shown to be useful for the treatment of certain types of cancer.
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| 申请公布号 |
US2007249610(A1) |
申请公布日期 |
2007.10.25 |
| 申请号 |
US20070737787 |
申请日期 |
2007.04.20 |
| 申请人 |
BRISTOL-MYERS SQUIBB COMPANY |
发明人 |
CRISPINO GERARD A.;HAMEDI MOURAD;LAPORTE THOMAS L.;THORNTON JOHN E.;PESTI JAAN A.;XU ZHONGMIN;LOBBEN PAUL C.;LEAHY DAVID K.;MUSLEHIDDINOGLU JALE;LAI CHIAJEN;SPANGLER LORI A.;DISCORDIA ROBERT P. |
| 分类号 |
A61K31/53;C07D487/04 |
主分类号 |
A61K31/53 |
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