| 摘要 |
The present invention discloses a selective culture medium for detecting MRSA and selective drug or multidrug resistant microorganisms where the expression of said (multi)drug resistance is by virtue of the production by said microorganisms of ß-lactamase enzymes. The medium comprises : (i) a broad spectrum antibiotic capable of selectively inhibiting growth/replication of (a) organisms that do not produce ß-lactamase enzymes, (b) organisms that while producing ß-lactamase do not exhibit an ESBL or AmpC phenotype and (c) Methicillin-susceptible S. aureus, and (ii) a compound capable of inducing production of ß-lactamases in an organism, and which compound is included at a concentration that is subinhibitory for growth of said microorganism. Also provided are a method and kit for selectively isolating any MRSA and/or ESBL or AmpC ß-lactamase producing microorganisms present in a sample using the selective culture medium. |
