发明名称 Cyanoamide compounds useful as malonyl-CoA decarboxylase inhibitors
摘要 The present invention provides methods for the use of compounds as depicted by structure I, pharmaceutical compositions containing the same, and methods for the prophylaxis, management and treatment of metabolic diseases and diseases modulated by MCD inhibition. The compounds disclosed in this invention are useful for the prophylaxis, management and treatment of diseases involving in malonyl-CoA regulated glucose/fatty acid metabolism pathway. In particular, these compounds and pharmaceutical composition containing the same are indicated in the prophylaxis, management and treatment of cardiovascular diseases, diabetes, cancer and obesity
申请公布号 US7285562(B2) 申请公布日期 2007.10.23
申请号 US20040900957 申请日期 2004.07.28
申请人 CHUGAI SEIYAKU KABUSHIKI KAISHA 发明人 KAFKA MARK D.;WILSON MARK E.;RUSSELL ANNA;LOPASCHUK GARY D.;DYCK JASON R.
分类号 A61K31/44;A61K31/415;A61K31/425;A61P3/04;A61P3/10;A61P9/00;A61P9/10;C07D277/70;C07D417/12 主分类号 A61K31/44
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