发明名称 CRYSTALLINE 1H-IMIDAZO[4,5-B]PYRIDIN-5-AMINE,7-[5-[(CYCLOHEXYLMETHYLAMINO)-METHYL]-1H-INDOL-2-YL]-2-METHYL, SULFATE (1:1), TRIHYDRATE AND ITS PHARMACEUTICAL USES
摘要 The invention relates to crystalline 1W-lmidazo[4,5-d]pyridi'-5-amine, 7-[5-[(cyclohexylmethylamino)-methyl]-1H-indol-2-yl]-2-methylI sulfate (1:1), trihydrate, E6070, its method of preparation, and its therapeutic uses. Pharmaceutical compositions containing crystalline E6070 and a pharmaceutically acceptable carrier represent one embodiment of the invention. The invention also relates to methods for treating an inflammatory disorder, an autoimmune disorder, or a proliferative disorder comprising the step of administering to a patient in need thereof a therapeutically effective amount of crystalline E6070.
申请公布号 KR20070102724(A) 申请公布日期 2007.10.19
申请号 KR20077019970 申请日期 2006.02.01
申请人 EISAI CO., LTD. 发明人 CHASE CHARLES E.;KUSHIDA IKUO
分类号 C07D471/04;A61K31/437;A61P29/00;A61P35/00 主分类号 C07D471/04
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