发明名称 |
METHOD FOR SUPPRESSING A FRET SIGNAL, FRET SIGNAL SUPPRESSOR AGENTS AND USE IN A METHOD FOR MULTIPLEXING BIOLOGICAL EVENTS |
摘要 |
The invention relates to a method for multiplexing biological events in a biological sample, characterized in that it comprises the suppression of the FRET emitted by the reaction medium containing at least two pairs of fluorescent FRET partner conjugates, each being specific for one of the biological events studied. This suppression of the emitted FRET is carried out by introducing into the medium a FRET signal suppressor agent characterized in that it has a domain for binding to a fluorophore which is a member of a pair of FRET partners and is capable of suppressing the FRET signal emitted when the two partners are in proximity to one another. |
申请公布号 |
WO2007116069(A1) |
申请公布日期 |
2007.10.18 |
申请号 |
WO2007EP53479 |
申请日期 |
2007.04.10 |
申请人 |
CIS BIO INTERNATIONAL;MATHIS, GERARD;TRINQUET, ERIC;ALBERTI, PATRIZIA;LAGET, MICHEL |
发明人 |
MATHIS, GERARD;TRINQUET, ERIC;ALBERTI, PATRIZIA;LAGET, MICHEL |
分类号 |
G01N33/542;C12Q1/68;G01N33/58 |
主分类号 |
G01N33/542 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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